Cover your work area with plastic and consider covering the floor too, as this is a messy project. Wear disposable gloves.
Spray paint the wood with a white gloss to use as a base.
Raise the wood on a couple of blocks or anything to have the paint drip off.
Pour some craft paints into small cups about 1/3 of the way full.
Add some pouring medium in the same amount so you have a 50/50 mix.
Add a few drops of the silicone. This is what makes the magic happen by repelling the others and creating interesting patterns.
Stir each cup well.
Next, make a dirty pour by combining the small cups into a larger cup.
Next, use one hand to hold the tray as you flip the cup upside down.
Then slowly lift the cup up, allowing the paint to pour onto the surface.
Move the tray around, tipping it back and forth, allowing the paint to run over the wood covering as much as you can or want.
Add a second pour if desired.
Also, consider using white on the outer edges to give your piece some white space.
Use any leftover paint from the cups to add color here or there and cover the edges if needed.
Allow the tray to dry for a day or two.
Once completely dry, give it 1-2 coats of polyurethane.
Screw in drawer pulls for handles.